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• Visualize the cellular heterogeneity of tissues and solid tumors with the multiplexing and spatial capabilities of the RNAscope Multiplex Fluorescent assay

• Specific and sensitive biomarker validation to accelerate translation of assays into the clinic

• Morphology-based biodistribution analysis of AAV vector and transgene expression

• CAR-T and TCR-T cell tumor infiltration and activity assays

• Detection of splice variants, point mutations and short target sequences with BaseScope ISH assays

• Co-stain with cell-type markers using our ISH/IHC Co-Detection workflow

• PAS’s quality-controlled tissue bank including solid tumors, diseased and normal human tissues, and TMAs

• RNAscope image analysis offerings for quantitative approaches to scoring

Learn how experts in the field of Oncology have utilized the RNAscope, BaseScope™ and Co-Detection Workflow Assays to address pertinent questions in their research.

The Bio-Techne Genomics Oncology Summit will be broadcast across three worldwide regions - Select your preferred Webinar Time in the registration form.

Introducing ACD's new/ novel chromogenic in situ hybridization assay for high-resolution detection of DNA copy number and structural variations- DNAscope Assays.

DNA ISH is a spatial profiling tool based on hybridizing labelled complementary probes to the target DNA inside the cell nucleus to visualize any genetic alterations in tissues. Learn how current limitations of the DNA ISH assay such as  limited morphological detail, difficult interpretation and low resolution detection due to larger probe sizes  are addressed by the new assay. The DNAscope chromogenic duplex (red/blue) staining allows researchers to use a standard bright-field microscope to visualize and quantify gene copy number variations (amplifications/deletions) and gene rearrangements/fusions in tissues with spatial and morphological context at single cell resolution.

• Spatial Visualization of any DNA target: Proven “double-Z” probe design and signal amplification system of RNAscope, enabling rapid and flexible probe development
• ​Unparalleled performance in detecting small genomic regions/single gene locus ​- Amplify target-specific signals but not background noise from non-specific hybridization
• Easy Interpretation and high throughput data analysis - Permanent chromogenic signal and superior morphological context