2019 Oct 15 - Pancreatic Cancer Therapeutic Target Visualized Using In Situ Hybridization
Yu Shi, Ph.D.
Staff Scientist, Salk Institute for Biological Sciences
Anushka Dikshit, Ph.D.
Applications Scientist, Advanced Cell Diagnostics

The complex nature of tumors not only makes them difficult to study in the lab but problematic when developing therapies to combat their growth. Visualizing altered gene expression within the tumor with spatial context often provides the first link to cellular function and potential biomarker identification. Traditional methods of analyzing gene expression, such as RT-PCR and microarrays, often fail to detect clinically relevant responses due to extraction based methodologies. When studying aggressive cancers such as pancreatic ductal adenocarcinoma (PDAC), the sensitivity and spatial resolution provided by in situ hybridization is essential to identifying critical changes in tumor cells that may aid the drug discovery process.

In this GEN webinar, we will hear about new PDAC research showing that the cytokine leukemia inhibitory factor (LIF) key paracrine factor from activated pancreatic stellate cells acting on cancer cells. Moreover, our expert panelist from the Salk Institute for Biological Studies, Yu Shi, PhD, will also describe how LIF promotes PDAC progression and facilitates its chemoresistance at advanced stages, as well as the potential for LIF as an interventional target for PDAC therapy.

Learning Objectives:

Watch the On-Demand Version Here

Contact Us

Complete one of the three forms below and we will get back to you.

For Quote Requests, please provide more details in the Contact Sales form below

Advanced Cell Diagnostics

Our new headquarters office starting May 2016:

7707 Gateway Blvd.  
Newark, CA 94560
Toll Free: 1 (877) 576-3636
Phone: (510) 576-8800
Fax: (510) 576-8798



19 Barton Lane  
Abingdon Science Park
OX14 3NB
United Kingdom
Phone 2: +44 1235 529449
Fax: +44 1235 533420


Advanced Cell Diagnostics China

20F, Tower 3,
Raffles City Changning Office,
1193 Changning Road, Shanghai 200051

Web: www.acdbio.com/cn

For general information: Info.ACD@bio-techne.com
For place an order: order.ACD@bio-techne.com
For product support: support.ACD@bio-techne.com
For career opportunities: hr.ACD@bio-techne.com