In Situ Hybridization, RNA-ISH

RNA expression
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Revolutionary RNAscope^® and BaseScope™ Assays
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Specific
Amplifies signal and simultaneously suppress noise
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Sensitive
Detects single RNA molecules
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Context
Detects RNA within conserved tissue or cell morphology
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Detect, localize and quantify vector and therapeutic transgenes

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Visualize and quantify expression of multiple checkpoint and immune cell markers

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Assess drug safety with unmatched sensitivity and specificity for any target in any tissue for any species

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Species-specific gene expression profiling of patient-derived xenograft tumors

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RNA expression of SCHLAP1 gene in human prostate cancer tissue using RNAscope<sup>®</sup> 2.5 HD Assay Brown RNA in situ hybridization (ISH)

RNA expression of SCHLAP1 gene in human prostate cancer tissue using RNAscope^® 2.5 HD Assay Brown

RNA expression of PCGEM1 gene in human prostate cancer tissue using RNAscope<sup>®</sup> 2.5 HD Assay Brown RNA in situ hybridization (ISH)

RNA expression of PCGEM1 gene in human prostate cancer tissue using RNAscope^® 2.5 HD Assay Brown

Expression of prostate cancer biomarker TP63 RNA (red dots) in human prostate cancer tissue, RNA in situ hybridization (ISH) using RNAscope<sup>®</sup> 2.0 HD Reagent Kit-RED

Expression of TP63 RNA (red dots) in human prostate cancer tissue, RNA in situ hybridization (ISH) using RNAscope^® 2.0 HD Reagent Kit-RED

Expression of prostate cancer biomarker PCA3 RNA (brown dots) in human prostate cancer tissue, RNA in situ hybridization (ISH) using RNAscope<sup>®</sup> 2.0 HD Reagent Kit-BROWN

Expression of PCA3 RNA (brown dots) in human prostate cancer tissue, RNA in situ hybridization (ISH) using RNAscope^® 2.0 HD Reagent Kit-BROWN

RNAscope<sup>®</sup> 2.5 LS Red - Prostate Cancer - PPIB

in situ hybridization of PPIB in prostate cancer tissue with RNAscope^® 2.5 LS Reagent Kit - RED

Expression of TP63 RNA (red dots) in human prostate cancer tissue, RNA in situ hybridization (ISH) using RNAscope^® 2.0 HD Reagent Kit-RED

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What to Buy

Step-by-step instructions to help you find the right products and accessories, learn best practices and get the best results from your assay.

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Let us run your Biomarker assays

Get high quality gene expression data in just a few weeks.

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Work smarter - Not harder

Sigal et al. used 46 RNAscope^® probes to thoroughly characterize the gastric antral gland stem cell niche.

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Mark the Pathway

Analyze all genes of a pathway with RNAscope^® ISH assays e.g. WNT/ β-catenin pathway | JAK/STAT signaling pathway | Akt Signaling Pathway.

Visualize all genes of a pathway

Validate your data

Use RNAscope^® ISH as a validation tool applied downstream of discoveries made with NGS, Microarrays, NanoString nCounter.

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Visualize the invisible

Use RNAscope^® assays to detect & visualize long non-coding RNA.

Visualize targets like long non-coding RNAs

Stay curious for new discoveries

Use RNAscope^® assays to detect and characterize new markers and targets.

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Combine for Divine

Analyze RNA and protein simultaneously with ISH & IHC on the same tissue section.

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Get Advice from Experts

Watch webinars for tips & tricks or presentations from our customers.

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Keep calm and read the famous manual

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Take cellfies not selfies

View examples of RNA visualization with our RNAscope^® products.

See examples of gene expressions in different tissues

Reveal in true colors

Detect up to four targets - take advantage of the RNAscope^® multiplexing capability.

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Detect, localize and quantify vector and therapeutic transgenes

Visualize and quantify expression of multiple checkpoint and immune cell markers

Assess drug safety with unmatched sensitivity and specificity for any target in any tissue for any species

Species-specific gene expression profiling of patient-derived xenograft tumors

Prostate Cancer Biomarker Data

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What to Buy

Let us run your Biomarker assays

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