In Situ Hybridization, RNA-ISH

HiPlex v2 Assay
Enhancing Your Spatial Genomics Story
Learn more
Spatial is in our DNA
Launching novel chromogenic DNAscope Duplex assay!
Learn more
Multi-omic profiling in situ
Introducing the New RNA-Protein Co-Detection Assays
Learn more
ASO, miRNA, and siRNA Detection with Spatial & Morphological Context
Learn more
RNAscope™
in situ hybridization probes for COVID-19 coronavirus are available
Order Probes Learn more
RNA expression
like you've never
seen it before
Revolutionary RNAscope^® and BaseScope™ Assays
Learn more Watch the video
area
Specific
Amplifies signal and simultaneously suppress noise
area
Sensitive
Detects single RNA molecules
area
Context
Detects RNA within conserved tissue or cell morphology
Expand your capabilities
with
The RNAscope^® HiPlex Assay
Learn more
Experience a new era of spatial genomics with the BaseScope™ Assay
Learn more
PROFESSIONAL ASSAY SERVICES
Dedicated RNAscope™ ISH Provider
Learn more Watch the video

Biopharma Feature

Detect, localize and quantify vector and therapeutic transgenes

With RNAscope^® and BaseScope™ Assays

Learn More

Biopharma Feature

Visualize and quantify expression of multiple checkpoint and immune cell markers

With RNAscope^® and BaseScope™ Assays

Learn More

Biopharma Feature

Assess drug safety with unmatched sensitivity and specificity for any target in any tissue for any species

With RNAscope^® Assays

Learn More

Biopharma Feature

Species-specific gene expression profiling of patient-derived xenograft tumors

With RNAscope^® Assays

Learn More

Expression of LOXL2 RNA (brown dots) in human colorectal cancer tissue, RNA in situ hybridization (ISH) using RNAscope<sup>®</sup> 2.0 HD Reagent Kit-BROWN

Expression of LOXL2 RNA (brown dots) in human colorectal cancer tissue, RNA in situ hybridization (ISH) using RNAscope^® 2.0 HD Reagent Kit-BROWN

Expression of SHH RNA (brown dots) in human colorectal cancer tissue, RNA in situ hybridization (ISH) using RNAscope<sup>®</sup> 2.0 HD Reagent Kit-BROWN

Expression of SHH RNA (brown dots) in human colorectal cancer tissue, RNA in situ hybridization (ISH) using RNAscope^® 2.0 HD Reagent Kit-BROWN

Expression of AREG RNA (brown dots) in human lung cancer tissue, RNA in situ hybridization (ISH) using RNAscope<sup>®</sup> 2.0 HD Reagent Kit-BROWN

Expression of AREG RNA (brown dots) in human lung cancer tissue, RNA in situ hybridization (ISH) using RNAscope^® 2.0 HD Reagent Kit-BROWN

Expression of EREG RNA (brown dots) in human lung cancer tissue, RNA in situ hybridization (ISH) using RNAscope<sup>®</sup> 2.0 HD Reagent Kit-BROWN

Expression of EREG RNA (brown dots) in human lung cancer tissue, RNA in situ hybridization (ISH) using RNAscope^® 2.0 HD Reagent Kit-BROWN

Expression of FGFR1 RNA (brown dots) in human ovarian cancer tissue, RNA in situ hybridization (ISH) using RNAscope<sup>®</sup> 2.0 HD Reagent Kit-BROWN

Expression of FGFR1 RNA (brown dots) in human ovarian cancer tissue, RNA in situ hybridization (ISH) using RNAscope^® 2.0 HD Reagent Kit-BROWN

Expression of VEGFR2 RNA (brown dots) in human renal cell cancer tissue, RNA in situ hybridization (ISH) using RNAscope<sup>®</sup> 2.0 HD Reagent Kit-BROWN

Expression of VEGFR2 RNA (brown dots) in human renal cell cancer tissue, RNA in situ hybridization (ISH) using RNAscope^® 2.0 HD Reagent Kit-BROWN

Today's Featured Data

Cancer Biomarkers

See application

Upcoming Events

Webinar

26

July, 2022

2022 Jul 26 - Visualization and Analysis of RNAscope™ Results using ...

View details

Conference

15

September, 2022

Spatial Biology US...

View details

Conference

08

October, 2022

College of American Pathologists (CAP)...

View details

Conference

25

October, 2022

American Society of Human Genetics...

View details

Conference

10

November, 2022

SITC’s 37th Annual Meeting ...

View details

View all

What to Buy

Step-by-step instructions to help you find the right products and accessories, learn best practices and get the best results from your assay.

Go to Buying Guide

Let us run your Biomarker assays

Get high quality gene expression data in just a few weeks.

Learn more

Work smarter - Not harder

Sigal et al. used 46 RNAscope^® probes to thoroughly characterize the gastric antral gland stem cell niche.

See publication

Mark the Pathway

Analyze all genes of a pathway with RNAscope^® ISH assays e.g. WNT/ β-catenin pathway | JAK/STAT signaling pathway | Akt Signaling Pathway.

Visualize all genes of a pathway

Validate your data

Use RNAscope^® ISH as a validation tool applied downstream of discoveries made with NGS, Microarrays, NanoString nCounter.

See publications

Visualize the invisible

Use RNAscope^® assays to detect & visualize long non-coding RNA.

Visualize targets like long non-coding RNAs

Stay curious for new discoveries

Use RNAscope^® assays to detect and characterize new markers and targets.

See publication on novel targets

Combine for Divine

Analyze RNA and protein simultaneously with ISH & IHC on the same tissue section.

Learn more on dual ISH/IHC

Get Advice from Experts

Watch webinars for tips & tricks or presentations from our customers.

Browse all webinars

Keep calm and read the famous manual

See all available manuals, check-lists and supporting literature.

Browse all manuals & documents

Take cellfies not selfies

View examples of RNA visualization with our RNAscope^® products.

See examples of gene expressions in different tissues

Reveal in true colors

Detect up to four targets - take advantage of the RNAscope^® multiplexing capability.

See all multiplexing publications

Search form

Detect, localize and quantify vector and therapeutic transgenes

Visualize and quantify expression of multiple checkpoint and immune cell markers

Assess drug safety with unmatched sensitivity and specificity for any target in any tissue for any species

Species-specific gene expression profiling of patient-derived xenograft tumors

Cancer Biomarkers

Upcoming Events

What to Buy

Let us run your Biomarker assays

Advanced Cell Diagnostics

Bio-Techne