In Situ Hybridization, RNA-ISH

Spatial is in our DNA
Launching novel chromogenic DNAscope Duplex assay!
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Multi-omic profiling in situ
Introducing the New RNA-Protein Co-Detection Assays
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ASO, miRNA, and siRNA Detection with Spatial & Morphological Context
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RNAscope™
in situ hybridization probes for COVID-19 coronavirus are available
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RNA expression
like you've never
seen it before
Revolutionary RNAscope^® and BaseScope™ Assays
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area
Specific
Amplifies signal and simultaneously suppress noise
area
Sensitive
Detects single RNA molecules
area
Context
Detects RNA within conserved tissue or cell morphology
Expand your capabilities
with
The RNAscope^® HiPlex Assay
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Experience a new era of spatial genomics with the BaseScope™ Assay
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PROFESSIONAL ASSAY SERVICES
Dedicated RNAscope™ ISH Provider
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Biopharma Feature

Detect, localize and quantify vector and therapeutic transgenes

With RNAscope^® and BaseScope™ Assays

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Biopharma Feature

Visualize and quantify expression of multiple checkpoint and immune cell markers

With RNAscope^® and BaseScope™ Assays

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Biopharma Feature

Assess drug safety with unmatched sensitivity and specificity for any target in any tissue for any species

With RNAscope^® Assays

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Biopharma Feature

Species-specific gene expression profiling of patient-derived xenograft tumors

With RNAscope^® Assays

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Detection of IL21R in human breast cancer using RNAscope 2.5 HD Brown Assay

Detection of IL21A in human ovarian cancer using RNAscope 2.5 HD Brown Assay

Simultaneous detection of CTLA4 (red) and PD-L1 (green) in NSCLC tissue using RNAScope 2.5 HD Duplex Assay

Simultaneous detection of LAG3 (red) and PD-L1 (green) in NSCLC tissue using RNAScope 2.5 HD Duplex Assay

Simultaneous detection of PD1 (red) and PD-L1 (green) in NSCLC tissue using RNAScope 2.5 HD Duplex Assay

Today's Featured Data

Immuno-oncology Genes

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Upcoming Events

Webinar

22

June, 2021

2021 June 22 - Resolving Brain Tissues with Spatial Transcriptomics: A...

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Webinar

28

June, 2021

2021 June 28 - A new era of RNA detection: Exploring new technologies ...

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Webinar

29

June, 2021

2021 June 29 - ACD Support Webinar - Probe Design Overview & Applicati...

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Conference

25

September, 2021

College of American Pathology...

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Conference

18

October, 2021

American Society for Human Genetics...

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Conference

10

November, 2021

Society for Immunotherapy of Cancer...

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Conference

13

November, 2021

Society for Neuroscience’s 50th Annual Meeting...

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Conference

16

November, 2021

Association for Molecular Pathology...

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Conference

30

November, 2021

California Society for Pathologists 4th Annual Meeting...

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What to Buy

Step-by-step instructions to help you find the right products and accessories, learn best practices and get the best results from your assay.

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Let us run your Biomarker assays

Get high quality gene expression data in just a few weeks.

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Work smarter - Not harder

Sigal et al. used 46 RNAscope^® probes to thoroughly characterize the gastric antral gland stem cell niche.

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Mark the Pathway

Analyze all genes of a pathway with RNAscope^® ISH assays e.g. WNT/ β-catenin pathway | JAK/STAT signaling pathway | Akt Signaling Pathway.

Visualize all genes of a pathway

Validate your data

Use RNAscope^® ISH as a validation tool applied downstream of discoveries made with NGS, Microarrays, NanoString nCounter.

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Visualize the invisible

Use RNAscope^® assays to detect & visualize long non-coding RNA.

Visualize targets like long non-coding RNAs

Stay curious for new discoveries

Use RNAscope^® assays to detect and characterize new markers and targets.

See publication on novel targets

Combine for Divine

Analyze RNA and protein simultaneously with ISH & IHC on the same tissue section.

Learn more on dual ISH/IHC

Get Advice from Experts

Watch webinars for tips & tricks or presentations from our customers.

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Keep calm and read the famous manual

See all available manuals, check-lists and supporting literature.

Browse all manuals & documents

Take cellfies not selfies

View examples of RNA visualization with our RNAscope^® products.

See examples of gene expressions in different tissues

Reveal in true colors

Detect up to four targets - take advantage of the RNAscope^® multiplexing capability.

See all multiplexing publications

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Detect, localize and quantify vector and therapeutic transgenes

Visualize and quantify expression of multiple checkpoint and immune cell markers

Assess drug safety with unmatched sensitivity and specificity for any target in any tissue for any species

Species-specific gene expression profiling of patient-derived xenograft tumors

Immuno-oncology Genes

Upcoming Events

What to Buy

Let us run your Biomarker assays

Advanced Cell Diagnostics

Bio-Techne