In Situ Hybridization, RNA-ISH

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Available for >13,000 targets across >140 species including gene families and signaling pathways targets. Probes for new targets available in 2 weeks.

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Biopharma Feature

Detect, localize and quantify vector and therapeutic transgenes

With RNAscope^® and BaseScope™ Assays

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Biopharma Feature

Visualize and quantify expression of multiple checkpoint and immune cell markers

With RNAscope^® and BaseScope™ Assays

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Biopharma Feature

Assess drug safety with unmatched sensitivity and specificity for any target in any tissue for any species

With RNAscope^® Assays

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Biopharma Feature

Species-specific gene expression profiling of patient-derived xenograft tumors

With RNAscope^® Assays

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Expression of prostate cancer biomarker TP63 RNA (red dots) in human prostate cancer tissue, RNA in situ hybridization (ISH) using RNAscope<sup>®</sup> 2.0 HD Reagent Kit-RED

Expression of TP63 RNA (red dots) in human prostate cancer tissue, RNA in situ hybridization (ISH) using RNAscope^® 2.0 HD Reagent Kit-RED

RNAscope<sup>®</sup> 2.5 LS Red - Prostate Cancer - PPIB

in situ hybridization of PPIB in prostate cancer tissue with RNAscope^® 2.5 LS Reagent Kit - RED

Expression of prostate cancer biomarker PCA3 RNA (brown dots) in human prostate cancer tissue, RNA in situ hybridization (ISH) using RNAscope<sup>®</sup> 2.0 HD Reagent Kit-BROWN

Expression of PCA3 RNA (brown dots) in human prostate cancer tissue, RNA in situ hybridization (ISH) using RNAscope^® 2.0 HD Reagent Kit-BROWN

Expression of TP63 RNA (red dots) in human prostate cancer tissue, RNA in situ hybridization (ISH) using RNAscope^® 2.0 HD Reagent Kit-RED

RNA expression of PCGEM1 gene in human prostate cancer tissue using RNAscope<sup>®</sup> 2.5 HD Assay Brown RNA in situ hybridization (ISH)

RNA expression of PCGEM1 gene in human prostate cancer tissue using RNAscope^® 2.5 HD Assay Brown

RNA expression of SCHLAP1 gene in human prostate cancer tissue using RNAscope<sup>®</sup> 2.5 HD Assay Brown RNA in situ hybridization (ISH)

RNA expression of SCHLAP1 gene in human prostate cancer tissue using RNAscope^® 2.5 HD Assay Brown

Today's Featured Data

Prostate Cancer Biomarker Data

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Announcements

Literature

RNAscope^® Data Analysis Guide

Data analysis guidelines for several types of RNAscope^® staining results, including semi-quantitative and quantitative analysis methods.

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Webinar

CAR-T Cell Target Selection and Preclinical Safety Assessment with RNAscope^® ISH

Presented by James B. Rottman
Sr. Director, Translational Development, bluebird bio

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Featured

Overcome IHC Challenges with RNAscope^® Technology

Get outstanding sensitivity and detect biomarkers with ease.

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Upcoming Events

Conference

20

August, 2018

RNAscope^® Boot Camps in Seattle, WA...

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Seminar

20

August, 2018

RNAscope^® Seminar @ Alnylam (Cambridge, MA)...

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Webinar

28

August, 2018

Getting Started and Troubleshooting Tips for RNAscope^® and BaseScope�...

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Seminar

12

September, 2018

The RNAscope^® Assay Lunch & Learn + Boot Camp @ UCSF...

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What to Buy

Step-by-step instructions to help you find the right products and accessories, learn best practices and get the best results from your assay.

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Let us run your Biomarker assays

Get high quality gene expression data in just a few weeks.

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Work smarter - Not harder

Sigal et al. used 46 RNAscope^® probes to thoroughly characterize the gastric antral gland stem cell niche.

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Mark the Pathway

Analyze all genes of a pathway with RNAscope^® ISH assays e.g. WNT/ β-catenin pathway | JAK/STAT signaling pathway | Akt Signaling Pathway.

Visualize all genes of a pathway

Validate your data

Use RNAscope^® ISH as a validation tool applied downstream of discoveries made with NGS, Microarrays, NanoString nCounter.

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Visualize the invisible

Use RNAscope^® assays to detect & visualize long non-coding RNA.

Visualize targets like long non-coding RNAs

Stay curious for new discoveries

Use RNAscope^® assays to detect and characterize new markers and targets.

See publication on novel targets

Combine for Divine

Analyze RNA and protein simultaneously with ISH & IHC on the same tissue section.

Learn more on dual ISH/IHC

Get Advice from Experts

Watch webinars for tips & tricks or presentations from our customers.

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Keep calm and read the famous manual

See all available manuals, check-lists and supporting literature.

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Take cellfies not selfies

View examples of RNA visualization with our RNAscope^® products.

See examples of gene expressions in different tissues

Reveal in true colors

Detect up to four targets - take advantage of the RNAscope^® multiplexing capability.

See all multiplexing publications

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Detect, localize and quantify vector and therapeutic transgenes

Visualize and quantify expression of multiple checkpoint and immune cell markers

Assess drug safety with unmatched sensitivity and specificity for any target in any tissue for any species