In Situ Hybridization, RNA-ISH

RNA expression
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Revolutionary RNAscope^® and BaseScope™ Assays
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Specific
Amplifies signal and simultaneously suppress noise
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Sensitive
Detects single RNA molecules
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Context
Detects RNA within conserved tissue or cell morphology
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Experience a new era of spatial genomics with the BaseScope™ Assay
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Detect, localize and quantify vector and therapeutic transgenes

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Visualize and quantify expression of multiple checkpoint and immune cell markers

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Assess drug safety with unmatched sensitivity and specificity for any target in any tissue for any species

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Biopharma Feature

Species-specific gene expression profiling of patient-derived xenograft tumors

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RNA expression of HGF gene (jak stat signaling pathway) in liver patient-derived xenograph (DPX) sample using RNAscope 2.5 HD Brown Assay and probe 441421 RNA in situ hybridization (ISH)

RNA expression of HGF gene in liver patient-derived xenograph (DPX) sample using RNAscope 2.5 HD Brown Assay and probe 441421

RNA expression of EGFR gene (jak stat signaling pathway) in human liver patient-derived xenograph (DPX) sample using RNAscope 2.5 HD Brown Assay and probe 418731 RNA in situ hybridization (ISH)

RNA expression of EGFR gene in human liver patient-derived xenograph (DPX) sample using RNAscope 2.5 HD Brown Assay and probe 418731

RNA expression of IFNB1 gene (jak stat signaling pathway) in human lymphoma sample using RNAscope 2.0 HD Brown Assay and probe 417071 RNA in situ hybridization (ISH)

RNA expression of IFNB1 gene in human lymphoma sample using RNAscope 2.0 HD Brown Assay and probe 417071

RNA expression of JAK2 gene (jak stat signaling pathway) in human colon cancer sample using RNAscope 2.0 HD Brown Assay and probe 403791 RNA in situ hybridization (ISH)

RNA expression of JAK2 gene in human colon cancer sample using RNAscope 2.0 HD Brown Assay and probe 403791

RNA expression of JAK2 gene (jak stat signaling pathway) in human breast cancer sample using RNAscope 2.0 HD Brown Assay and probe 403791 RNA in situ hybridization (ISH)

RNA expression of JAK2 gene in human breast cancer sample using RNAscope 2.0 HD Brown Assay and probe 403791

RNA expression of IFNG gene (jak stat signaling pathway) in human vular cancer sample using RNAscope 2.5 HD Brown Assay and probe 310501 RNA in situ hybridization (ISH)

RNA expression of IFNG gene in human vular cancer sample using RNAscope 2.5 HD Brown Assay and probe 310501

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JAK STAT Signaling Pathway Genes

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What to Buy

Step-by-step instructions to help you find the right products and accessories, learn best practices and get the best results from your assay.

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Let us run your Biomarker assays

Get high quality gene expression data in just a few weeks.

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Work smarter - Not harder

Sigal et al. used 46 RNAscope^® probes to thoroughly characterize the gastric antral gland stem cell niche.

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Mark the Pathway

Analyze all genes of a pathway with RNAscope^® ISH assays e.g. WNT/ β-catenin pathway | JAK/STAT signaling pathway | Akt Signaling Pathway.

Visualize all genes of a pathway

Validate your data

Use RNAscope^® ISH as a validation tool applied downstream of discoveries made with NGS, Microarrays, NanoString nCounter.

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Visualize the invisible

Use RNAscope^® assays to detect & visualize long non-coding RNA.

Visualize targets like long non-coding RNAs

Stay curious for new discoveries

Use RNAscope^® assays to detect and characterize new markers and targets.

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Combine for Divine

Analyze RNA and protein simultaneously with ISH & IHC on the same tissue section.

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Get Advice from Experts

Watch webinars for tips & tricks or presentations from our customers.

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Keep calm and read the famous manual

See all available manuals, check-lists and supporting literature.

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Take cellfies not selfies

View examples of RNA visualization with our RNAscope^® products.

See examples of gene expressions in different tissues

Reveal in true colors

Detect up to four targets - take advantage of the RNAscope^® multiplexing capability.

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Detect, localize and quantify vector and therapeutic transgenes

Visualize and quantify expression of multiple checkpoint and immune cell markers

Assess drug safety with unmatched sensitivity and specificity for any target in any tissue for any species

Species-specific gene expression profiling of patient-derived xenograft tumors

JAK STAT Signaling Pathway Genes

Upcoming Events

What to Buy

Let us run your Biomarker assays

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