In Situ Hybridization, RNA-ISH

Multi-omic profiling in situ
Introducing the New RNA-Protein Co-Detection Assays
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ASO, miRNA, and siRNA Detection with Spatial & Morphological Context
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RNAscope™
in situ hybridization probes for COVID-19 coronavirus are available
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RNA expression
like you've never
seen it before
Revolutionary RNAscope^® and BaseScope™ Assays
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area
Specific
Amplifies signal and simultaneously suppress noise
area
Sensitive
Detects single RNA molecules
area
Context
Detects RNA within conserved tissue or cell morphology
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with
The RNAscope^® HiPlex Assay
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Experience a new era of spatial genomics with the BaseScope™ Assay
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Enable your RNAscope & BaseScope projects with the award-winning Pharma Assay Services
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Detect, localize and quantify vector and therapeutic transgenes

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Visualize and quantify expression of multiple checkpoint and immune cell markers

With RNAscope^® and BaseScope™ Assays

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Biopharma Feature

Assess drug safety with unmatched sensitivity and specificity for any target in any tissue for any species

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Biopharma Feature

Species-specific gene expression profiling of patient-derived xenograft tumors

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Expression of LOXL2 RNA (brown dots) in human colorectal cancer tissue, RNA in situ hybridization (ISH) using RNAscope<sup>®</sup> 2.0 HD Reagent Kit-BROWN

Expression of LOXL2 RNA (brown dots) in human colorectal cancer tissue, RNA in situ hybridization (ISH) using RNAscope^® 2.0 HD Reagent Kit-BROWN

Expression of SHH RNA (brown dots) in human colorectal cancer tissue, RNA in situ hybridization (ISH) using RNAscope<sup>®</sup> 2.0 HD Reagent Kit-BROWN

Expression of SHH RNA (brown dots) in human colorectal cancer tissue, RNA in situ hybridization (ISH) using RNAscope^® 2.0 HD Reagent Kit-BROWN

Expression of AREG RNA (brown dots) in human lung cancer tissue, RNA in situ hybridization (ISH) using RNAscope<sup>®</sup> 2.0 HD Reagent Kit-BROWN

Expression of AREG RNA (brown dots) in human lung cancer tissue, RNA in situ hybridization (ISH) using RNAscope^® 2.0 HD Reagent Kit-BROWN

Expression of EREG RNA (brown dots) in human lung cancer tissue, RNA in situ hybridization (ISH) using RNAscope<sup>®</sup> 2.0 HD Reagent Kit-BROWN

Expression of EREG RNA (brown dots) in human lung cancer tissue, RNA in situ hybridization (ISH) using RNAscope^® 2.0 HD Reagent Kit-BROWN

Expression of FGFR1 RNA (brown dots) in human ovarian cancer tissue, RNA in situ hybridization (ISH) using RNAscope<sup>®</sup> 2.0 HD Reagent Kit-BROWN

Expression of FGFR1 RNA (brown dots) in human ovarian cancer tissue, RNA in situ hybridization (ISH) using RNAscope^® 2.0 HD Reagent Kit-BROWN

Expression of VEGFR2 RNA (brown dots) in human renal cell cancer tissue, RNA in situ hybridization (ISH) using RNAscope<sup>®</sup> 2.0 HD Reagent Kit-BROWN

Expression of VEGFR2 RNA (brown dots) in human renal cell cancer tissue, RNA in situ hybridization (ISH) using RNAscope^® 2.0 HD Reagent Kit-BROWN

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Cancer Biomarkers

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Upcoming Events

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23

October, 2020

2020 Oct 23 - Application of RNAscope for Spatio-temporal Visualizatio...

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26

October, 2020

2020 Oct 26 - Knowledge Resource Series - Inflammation Applications...

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27

October, 2020

2020 Oct 27 - Visualize your RNA and RNA-Protein Co-Detection using RN...

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October, 2020

ASHG 2020 Virtual Conference...

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November, 2020

2020 Nov 2 - Knowledge Resource Series - Single-Cell Applications...

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November, 2020

2020 Nov 5 - ACD-NIH Virtual Seminar: Spatial Transcriptomic Analysis ...

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November, 2020

SITC 35th Anniversary 2020 - Virtual Conference...

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November, 2020

2020 Nov 11 - Spatial Mapping and in situ Confirmation of Gene Signatu...

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November, 2020

2020 Nov 17 - Spatial Expression Analyses Elucidates Mechanisms of cir...

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November, 2020

2020 Nov 20 - Companion Diagnostic and Biomarker Assay Development for...

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What to Buy

Step-by-step instructions to help you find the right products and accessories, learn best practices and get the best results from your assay.

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Let us run your Biomarker assays

Get high quality gene expression data in just a few weeks.

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Work smarter - Not harder

Sigal et al. used 46 RNAscope^® probes to thoroughly characterize the gastric antral gland stem cell niche.

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Mark the Pathway

Analyze all genes of a pathway with RNAscope^® ISH assays e.g. WNT/ β-catenin pathway | JAK/STAT signaling pathway | Akt Signaling Pathway.

Visualize all genes of a pathway

Validate your data

Use RNAscope^® ISH as a validation tool applied downstream of discoveries made with NGS, Microarrays, NanoString nCounter.

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Visualize the invisible

Use RNAscope^® assays to detect & visualize long non-coding RNA.

Visualize targets like long non-coding RNAs

Stay curious for new discoveries

Use RNAscope^® assays to detect and characterize new markers and targets.

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Combine for Divine

Analyze RNA and protein simultaneously with ISH & IHC on the same tissue section.

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Get Advice from Experts

Watch webinars for tips & tricks or presentations from our customers.

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Keep calm and read the famous manual

See all available manuals, check-lists and supporting literature.

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Take cellfies not selfies

View examples of RNA visualization with our RNAscope^® products.

See examples of gene expressions in different tissues

Reveal in true colors

Detect up to four targets - take advantage of the RNAscope^® multiplexing capability.

See all multiplexing publications

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Detect, localize and quantify vector and therapeutic transgenes

Visualize and quantify expression of multiple checkpoint and immune cell markers

Assess drug safety with unmatched sensitivity and specificity for any target in any tissue for any species

Species-specific gene expression profiling of patient-derived xenograft tumors

Cancer Biomarkers

Upcoming Events

What to Buy

Let us run your Biomarker assays

Advanced Cell Diagnostics

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