In Situ Hybridization, RNA-ISH

Biopharma Feature

Detect, localize and quantify vector and therapeutic transgenes

With RNAscope^® and BaseScope™ Assays

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Biopharma Feature

Visualize and quantify expression of multiple checkpoint and immune cell markers

With RNAscope^® and BaseScope™ Assays

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Biopharma Feature

Assess drug safety with unmatched sensitivity and specificity for any target in any tissue for any species

With RNAscope^® Assays

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Biopharma Feature

Species-specific gene expression profiling of patient-derived xenograft tumors

With RNAscope^® Assays

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WNT/β-catenin signaling pathway expression analysis RNA Expression CTNNB1 gene human renal carcinoma RNAscope LS 2.5 HD Brown Assay

RNA Expression of CTNNB1 in human renal carcinoma using RNAscope LS 2.5 HD Brown Assay

RNA expression of GSK3A gene (WNT B-Catenin signaling pathway) in human ovarian cancer TMA sample using RNAscope<sup>®</sup> 2.5 HD Brown Assay

RNA expression of GSK3A gene in human ovarian cancer TMA sample using RNAscope^® 2.5 HD Brown Assay

WNT/β-catenin signaling pathway expression analysis RNA expression of GSK3A in human esophageal cancer RNAscope<sup>®</sup> 2.5 HD Brown Assay

RNA expression of GSK3A gene in human esophageal cancer TMA sample using RNAscope^® 2.5 HD Brown Assay

RNA expression of GSK3B gene (WNT B-Catenin signaling pathway) in human ovarian cancer TMA sample using RNAscope<sup>®</sup> 2.5 HD Brown Assay

RNA expression of GSK3B gene in human ovarian cancer TMA sample using RNAscope^® 2.5 HD Brown Assay

RNA expression of GSK3B gene (WNT B-Catenin signaling pathway) in human esophageal cancer TMA sample using RNAscope<sup>®</sup> 2.5 HD Brown Assay

RNA expression of GSK3B gene in human esophageal cancer TMA sample using RNAscope^® 2.5 HD Brown Assay

RNA expression of MYC gene (WNT B-Catenin signaling pathway) in human liver cancer sample using RNAscope<sup>®</sup> 2.5 HD Brown Assay

RNA expression of MYC gene in human liver cancer sample using RNAscope^® 2.5 HD Brown Assay

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Wnt / b-Catenin Signaling Pathway Genes

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What to Buy

Step-by-step instructions to help you find the right products and accessories, learn best practices and get the best results from your assay.

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Let us run your Biomarker assays

Get high quality gene expression data in just a few weeks.

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Work smarter - Not harder

Sigal et al. used 46 RNAscope^® probes to thoroughly characterize the gastric antral gland stem cell niche.

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Mark the Pathway

Analyze all genes of a pathway with RNAscope^® ISH assays e.g. WNT/ β-catenin pathway | JAK/STAT signaling pathway | Akt Signaling Pathway.

Visualize all genes of a pathway

Validate your data

Use RNAscope^® ISH as a validation tool applied downstream of discoveries made with NGS, Microarrays, NanoString nCounter.

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Visualize the invisible

Use RNAscope^® assays to detect & visualize long non-coding RNA.

Visualize targets like long non-coding RNAs

Stay curious for new discoveries

Use RNAscope^® assays to detect and characterize new markers and targets.

See publication on novel targets

Combine for Divine

Analyze RNA and protein simultaneously with ISH & IHC on the same tissue section.

Learn more on dual ISH/IHC

Get Advice from Experts

Watch webinars for tips & tricks or presentations from our customers.

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Keep calm and read the famous manual

See all available manuals, check-lists and supporting literature.

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Take cellfies not selfies

View examples of RNA visualization with our RNAscope^® products.

See examples of gene expressions in different tissues

Reveal in true colors

Detect up to four targets - take advantage of the RNAscope^® multiplexing capability.

See all multiplexing publications

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Detect, localize and quantify vector and therapeutic transgenes

Visualize and quantify expression of multiple checkpoint and immune cell markers

Assess drug safety with unmatched sensitivity and specificity for any target in any tissue for any species