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RNAscope Technology for Diagnostics

Advanced Cell Diagnostics (ACD), inventors of the innovative RNAscope™ in situ hybridization (ISH) Technology have over 30,000+ RNA probes, designed and ready to use, available for most research areas and applications. RNAscope ISH technology with its proprietary double Z probe design and reagents enable reliable detection of RNA biomarkers at a single molecule sensitivity within morphological context for FFPE tissues. With 40+ issued and pending patents, over 4000 publications and customers in many diagnostic, pharma and academic fields, RNAscope technology is primed for adoption by the clinical and companion diagnostic community.

RNAscope ISH for Diagnostics

ACD has partnered with Leica Biosystems to develop the fully automated RNAscope ISH technology, available for diagnostic use. The RNAscope ISH Technology has been optimized for diagnostic and clinical use on the BOND III Advanced Staining Clinical Platform. Please contact Leica Biosystems for more supporting information.

There are currently 16 ASR probes available: targeted for Albumin, CMV, EBV, HPV-6, HPV-11 (concentrate), HPV-16, HPV-18 (concentrate), HPV-31, HPV-31 (concentrate), HPV-33 (concentrate), Napsin-A, SARS-CoV-2, and TTF-1 covering a number of clinical disease states, as well as control probes: PPIB (Positive), UBC (Positive), and dapB (negative).

Ordering Information

Product Code

Product Name

Size

Status

Order

Detection Kits

DS9790

BOND RNAscope Detection Reagents - BROWN

Pre-filled BOND containers

GPR

Order via Leica

AR9773

BOND RNAscope Protease

Pre-filled BOND container

GPR

Order via Leica

Target probes

200440

RNAscope ISH Probe SARS-CoV-2

14 mLASR

Order via ACD

RS7750

ACD RNA ISH Probe CMV

14 mL

ASR

Order via Leica

RS7751

ACD RNA ISH Probe EBV

14 mL

ASR

Order via Leica

RS7752

ACD RNA ISH Probe Albumin

14 mL

ASR

Order via Leica

RS7753

ACD RNA ISH Probe TTF1

14 mL

ASR

Order via Leica

RS7754

ACD RNA ISH Probe Napsin A

14 mL

ASR

Order via Leica

RS7757

ACD RNA ISH Probe HPV-6

14 mLASR

Order via Leica

RS7758

ACD RNA ISH Probe HPV-16

14 mLASR

Order via Leica

RS7759

ACD RNA ISH Probe HPV-31

14 mLASR

Order via Leica

RS7860

ACD RNA ISH Probe (concentrate) HPV-11

80 µlASR

Order via Leica

RS7861

ACD RNA ISH Probe (concentrate) HPV-18

80 µlASR

Order via Leica

RS7862

ACD RNA ISH Probe (concentrate) HPV-31

80 µlASR

Order via Leica

RS7863

ACD RNA ISH Probe (concentrate) HPV-33

80 µl

ASR

Order via Leica

ISH Control Probes

RS7755

PPIB (Positive Control)

14 mL

ASR

Order via Leica

RS7756

dapB (Negative Control)

14 mL

ASR

Order via Leica

RS7760

ACD RNA ISH Probe UBC (Pos. Ctrl.)

14 mLASR

Order via Leica

Additional information is available via  Leica Biosystems .To learn more, please find the informational materials below:

Brochure

Leica Bond III ISH and IHC stainer and ACD's RNAscope

Download Brochure

Flyer

Leica Bond III and ACD RNAscope ISH Chromogenic Probes

Download Flyer

RNAscope ISH PROBE SARS-COV-2

Download Flyer

App Note

Leica Application Note – Implement and Walk Away

Download App Note

Pathologist Journal

One Slide, All the Answers - Dr. Monroe interview with Pathologist journal

Download Article

Partnership with Leica Biosystems

Take a look at our short video, describing our partnership and continued progress to advance clinical diagnostics via innovative technologies including RNA ISH.

Watch video

The ACD ASR Chromogenic ISH probes have been developed in partnership by both ACD and Leica Biosystems to be a fully-automated, plug and play RNA ISH that fits seamlessly with existing clinical laboratory equipment and workflows. The clinically proven standard protocol on the Bond III provides superior accuracy, reproducibility and reliability. The established chromogenic detection allows for standard bright-field review and analysis as preferred by pathologists, accustomed to reviewing IHC.

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Advanced Cell Diagnostics

Our new headquarters office starting May 2016:

7707 Gateway Blvd.  
Newark, CA 94560
Toll Free: 1 (877) 576-3636
Phone: (510) 576-8800
Fax: (510) 576-8798

 

Bio-Techne

19 Barton Lane  
Abingdon Science Park
Abingdon
OX14 3NB
United Kingdom
Phone 2: +44 1235 529449
Fax: +44 1235 533420

 

 

Advanced Cell Diagnostics China

Building 15, No. 26 Xihuan South Road
Beijing Economic-Technological Development Area
Beijing, China, Zip code: 100176

400-966-1796
info_china.ACD@bio-techne.com
For general information: Leon.Li@bio-techne.com
Web: www.acdbio.com/cn

For general information: Info.ACD@bio-techne.com
For place an order: order.ACD@bio-techne.com
For product support: support.ACD@bio-techne.com
For career opportunities: hr.ACD@bio-techne.com