Advanced Cell Diagnostics (ACD), inventors of the innovative RNAscope™ in situ hybridization (ISH) Technology have over 30,000+ RNA probes, designed and ready to use, available for most research areas and applications. RNAscope ISH technology with its proprietary double Z probe design and reagents enable reliable detection of RNA biomarkers at a single molecule sensitivity within morphological context for FFPE tissues. With 40+ issued and pending patents, over 4000 publications and customers in many diagnostic, pharma and academic fields, RNAscope technology is primed for adoption by the clinical and companion diagnostic community.
RNAscope ISH for Diagnostics
ACD has partnered with Leica Biosystems to develop the fully automated RNAscope ISH technology, available for diagnostic use. The RNAscope ISH Technology has been optimized for diagnostic and clinical use on the BOND III Advanced Staining Clinical Platform. Please contact Leica Biosystems for more supporting information.
There are currently 16 ASR probes available: targeted for Albumin, CMV, EBV, HPV-6, HPV-11 (concentrate), HPV-16, HPV-18 (concentrate), HPV-31, HPV-31 (concentrate), HPV-33 (concentrate), Napsin-A, SARS-CoV-2, and TTF-1 covering a number of clinical disease states, as well as control probes: PPIB (Positive), UBC (Positive), and dapB (negative).
Ordering Information
Product Code | Product Name | Size | Status | Order |
|---|---|---|---|---|
Detection Kits | ||||
DS9790 | BOND RNAscope Detection Reagents - BROWN | Pre-filled BOND containers | GPR | |
AR9773 | BOND RNAscope Protease | Pre-filled BOND container | GPR | |
Target probes | ||||
200440 | RNAscope ISH Probe SARS-CoV-2 | 14 mL | ASR | |
RS7750 | ACD RNA ISH Probe CMV | 14 mL | ASR | |
RS7751 | ACD RNA ISH Probe EBV | 14 mL | ASR | |
RS7752 | ACD RNA ISH Probe Albumin | 14 mL | ASR | |
RS7753 | ACD RNA ISH Probe TTF1 | 14 mL | ASR | |
RS7754 | ACD RNA ISH Probe Napsin A | 14 mL | ASR | |
RS7757 | ACD RNA ISH Probe HPV-6 | 14 mL | ASR | |
RS7758 | ACD RNA ISH Probe HPV-16 | 14 mL | ASR | |
RS7759 | ACD RNA ISH Probe HPV-31 | 14 mL | ASR | |
RS7860 | ACD RNA ISH Probe (concentrate) HPV-11 | 80 µl | ASR | |
RS7861 | ACD RNA ISH Probe (concentrate) HPV-18 | 80 µl | ASR | |
RS7862 | ACD RNA ISH Probe (concentrate) HPV-31 | 80 µl | ASR | |
RS7863 | ACD RNA ISH Probe (concentrate) HPV-33 | 80 µl | ASR | |
ISH Control Probes | ||||
RS7755 | PPIB (Positive Control) | 14 mL | ASR | |
RS7756 | dapB (Negative Control) | 14 mL | ASR | |
RS7760 | ACD RNA ISH Probe UBC (Pos. Ctrl.) | 14 mL | ASR | |
Additional information is available via Leica Biosystems .To learn more, please find the informational materials below:
Flyer
Pathologist Journal
One Slide, All the Answers - Dr. Monroe interview with Pathologist journal
Partnership with Leica Biosystems
Take a look at our short video, describing our partnership and continued progress to advance clinical diagnostics via innovative technologies including RNA ISH.
The ACD ASR Chromogenic ISH probes have been developed in partnership by both ACD and Leica Biosystems to be a fully-automated, plug and play RNA ISH that fits seamlessly with existing clinical laboratory equipment and workflows. The clinically proven standard protocol on the Bond III provides superior accuracy, reproducibility and reliability. The established chromogenic detection allows for standard bright-field review and analysis as preferred by pathologists, accustomed to reviewing IHC.
