Advanced Cell Diagnostics, inventors of the innovative RNAscope® ISH Technology have over 13,000+ RNA probes, designed and ready to use, available for most research areas and applications. RNAscope ® in situ hybridization technology with its proprietary double Z probe design and reagents enable reliable detection of RNA biomarkers at a single molecule sensitivity within morphological context for FFPE tissues. With 40+ issued and pending patents, over 800 publications and customers in many diagnostic, pharma and academic fields, RNAscope® technology is primed for adoption by the clinical and companion diagnostic community.
RNAscope® ISH for Diagnostics
Advanced Cell Diagnostics have partnered with Leica Biosystems to develop the fully automated RNAscope® ISH technology, available for diagnostic use. The RNAscope® ISH Technology has been optimized for diagnostic and clinical use on the Bond III Advanced Staining Clinical Platform. This will be marketed, sold and supported by Leica Biosystems.
There are currently 5 ASR probes available: targeted for Albumin, CMV, EBV, Napsin-A and TTF-1, covering a number of clinical disease states, as well as control probes: PPIB (Positive) and dapB (negative).
Ordering Information
Product Code | Product Name | Size | Status | Order |
|---|---|---|---|---|
RNA probes | ||||
RS7750 | CMV Probe | 14 mL | ASR | |
RS7751 | EBV Probe | 14 mL | ASR | |
RS7752 | Albumin Probe | 14 mL | ASR | |
RS7753 | TTF-1 Probe | 14 mL | ASR | |
RS7754 | Napsin A Probe | 14 mL | ASR | |
ISH Control Probes | ||||
RS7755 | PPIB (Positive Control) | 14 mL | ASR | |
RS7756 | dapB (Negative Control) | 14 mL | ASR | |
Details and ordering information are available via Leica Biosystems directly, however, please find the informational brochures below:
Academic, pharmaceutical and biotechnology customers will still have access to our research use (RUO) RNAscope and BaseScope probes on the Leica Bond Rx System and the Ventana Medical Systems Discovery Ultra and XT Platforms (Automated Advanced Staining Platforms), which will continue to expand into new research areas.
Partnership with Leica Biosystems
Take a look at our short video, describing our partnership and continued progress to advance clinical diagnostics via innovative technologies including RNA ISH.
The ACD ASR Chromogenic ISH probes have been developed in partnership by both ACD and Leica Biosystems to be a fully-automated, plug and play RNA ISH that fits seamlessly with existing clinical laboratory equipment and workflows. The clinically proven standard protocol on the Bond III provides superior accuracy, reproducibility and reliability. The established chromogenic detection allows for standard bright-field review and analysis as preferred by pathologists, accustomed to reviewing IHC.
