2021 Aug 25 - Mapping Neuronal Gene Expression to Understand Pain
Ted Price, PhD
Eugene McDermott Professor Director, Center for Advanced Pain Studies University of Texas at Dallas
Watch Video:
Diana Tavares-Ferreira, PhD
Postdoctoral Fellow Center for Advanced Pain Studies University of Texas at Dallas
Stephanie Shiers, PhD
Postdoctoral Fellow Center for Advanced Pain Studies University of Texas at Dallas
Outline:
The human dorsal root ganglion (DRG) is the site of many sensory neurons, including pain-sensing neurons called nociceptors. Therefore, studying the DRG is important for understanding pain responses—especially chronic pain development. Researchers can characterize the DRG by mapping gene expression in its cells. In this webinar brought to you by ACD – a BioTechne brand, Ted Price, Diana Tavares-Ferreira, and Stephanie Shiers will discuss mapping the DRG to identify different neuronal subtypes, thereby aiding target identification and drug discovery with the ultimate goal of developing non-opioid painkillers.
Learning Objectives:
- Transcriptional differences in sensory neuron subtypes in the human DRG
- How differences in neuronal gene expression between species affect drug target development
- How researchers go from target identification to drug development
