2024 March 23 - Seminar | RNAscope: Current and Emerging Clinical Applications | In Situ Hybridization, RNA-ISH | ACDBio

2024 March 23 - Seminar | RNAscope: Current and Emerging Clinical Applications

Jordan Laser, MD

Senior Director, Clinical & Medical Aﬀairs Diagnostic and Genomics Segment, Bio-Techne

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Nidhi Aggarwal, MD

Divisions of Hematopathology and Molecular and Genomics Pathology, Department of Pathology, University of Pittsburgh

Rohit Mehra, MD

Clinical Professor of Pathology at Michigan Medicine and Faculty Member of the Michigan Center for Translational Pathology (MCTP)

Outline:

During this seminar, we explored the technology behind RNAscope, the highly sensitive and specific RNA in situ hybridization. Ranging in clinical applications from oncology to infectious diseases, RNAscope is fully automated on existing immunohistochemistry platforms providing clear answers while seamlessly fitting into existing anatomic pathology workflows. We will highlight RNAscope in supporting the evaluation of lymphomas, specifically via IgK, IgL and IGLL5 in situ hybridization as well as demonstrate the value of emerging markers in renal cell carcinomas.