RNAscope CE-IVD Detection

Advanced Cell Diagnostics (ACD), a Bio-Techne Brand, is the developer of the RNAscope In Situ Hybridization Detection System, now CE-IVD marked for clinical diagnostic use in Europe.  RNAscope is a robust technology that identifies RNA expression patterns and localization at the single cell level with spatial and morphologic context. The RNAscope technology is highly sensitive and specific due to its propriety double ZZ probe design, resulting in an extremely high signal-to-noise ratio of staining in FFPE tissues, allowing diagnostic pathologists to visualize, localize, and quantify biomarker expression simultaneously.  


ACD offers over 30,000 RUO probes for an extensive selection of biomarkers for a wide variety of applications that can expand the capabilities of your lab.


Anatomic Pathology Flyer

Panels of RNAscope Probes for the major areas of pathology*

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Click Here to Find Out More About Our Anatomic Pathology Panels


RNAscope ISH Fully Automated

ACD has partnered with Leica Biosystems to develop the fully automated BOND RNAscope Brown Detection Reagents for use on the BOND III Advanced Staining Platform. The BOND RNAscope Technology provides a plug-and-play RNA ISH solution that fits seamlessly with existing clinical lab workflows. The clinically proven standard protocol on the BOND-III provides superior accuracy, reproducibility, and reliability. Chromogenic detection allows for standard bright-field evaluation by pathologists, similar to IHC. The detection kit has been optimized for diagnostic and clinical use on the Bond III Advanced Staining Clinical Platform. BOND RNAscope Brown Detection Reagents will be marketed, sold and supported by Leica Biosystems.


Ordering Information

Product Code

Product Name




Detection System



Brown Detection

60 Slides


Order via Leica

Details and ordering information of BOND RNAscope Brown Detection System (DS9815) are available via Leica Biosystems , however, please find the informational brochures below:


Leica Bond III ISH and IHC stainer and ACD's RNAscope

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App Note

Leica Application Note – Implement and Walk Away

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Pathologist Journal

One Slide, All the Answers - Dr. Monroe interview with Pathologist journal

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Partnership with Leica Biosystems

Take a look at our short video, describing our partnership and continued progress to advance clinical diagnostics via innovative technologies including RNA ISH.

Watch video


Contact Us

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Advanced Cell Diagnostics

Our new headquarters office starting May 2016:

7707 Gateway Blvd.  
Newark, CA 94560
Toll Free: 1 (877) 576-3636
Phone: (510) 576-8800
Fax: (510) 576-8798



19 Barton Lane  
Abingdon Science Park
OX14 3NB
United Kingdom
Phone 2: +44 1235 529449
Fax: +44 1235 533420


Advanced Cell Diagnostics China

20F, Tower 3,
Raffles City Changning Office,
1193 Changning Road, Shanghai 200051

Web: www.acdbio.com/cn

For general information: Info.ACD@bio-techne.com
For place an order: order.ACD@bio-techne.com
For product support: support.ACD@bio-techne.com
For career opportunities: hr.ACD@bio-techne.com