2021 Jul 21 - A Highly Sensitive Chromogenic DNA in situ Hybridization Technology with Clinical and Diagnostic Potential
Xiao-Jun Ma, Ph.D.
Chief Scientific Officer, Advanced Cell Diagnostics, a Bio-Techne Brand
Watch Video:
Robert Monroe, MD, Ph.D.,
Chief Medical Officer, Advanced Cell Diagnostics, a Bio-Techne Brand
Outline:
Fluorescent in situ hybridization (ISH) is a common tool to detect and visualize specific DNA sequences in single cells. Current DNA ISH methods are inferior because they detect genes at low resolution due to long DNA probes and they require expensive, high resolution microscopes. This webinar will introduce DNAscopeTM, an innovative DNA ISH technology that employs a new probe design allowing for the precise targeting of small DNA stretches and convenient visualization under standard light microscopes.
Learning Objectives:
- How ‘double Z’ probe design promotes accurate target labeling
- How to detect DNA breaks and copy number variations
- The clinical potential of DNAscope for both pathology and diagnostic applications
