Visualize Gene Expression and Genetic Variations in situ with the RNAscope™ and BaseScopeTM ISH Technology
Advanced Cell Diagnostics’ RNAscope™ platform is fast becoming a routinely used method for gene expression analysis in situ, with over 580 peer-reviewed publications using this method. The RNAscope™ and BaseScopeTM assays are two highly sensitive and specific RNA in situ hybridization (ISH) methods to visualize gene expression and genetic variations in the tissue environment. Both assays provide single-cell and single-molecule RNA detection in the context of complex disease microenvironments. In this seminar the RNAscope™ and BaseScopeTM ISH technology and illustrations of published applications will be presented:
- Detect mRNAs and lncRNAs at single molecule sensitivity by RNAscope™ Assay
- Pinpoint expression of novel RNAs of interest
- Target specific splice junctions by BaseScopeTM Assay
- Identify point mutations or gene editing by BaseScopeTM Assay
- Detect short sequences with BaseScopeTM Assay
- Distinguish specific homologues, paralogues, and orthologues by RNAscope™ or BaseScopeTM Assays
- Perform single cell analysis with morphological information in FFPE or frozen tissues
Location: Learner Research Institute, NC 1-202