RNAscope™ and BaseScope™ in situ Hybridization Platforms

Visual detection and quantification of AAV and LV vector biodistribution and transgene expression in preclinical animal models with RNAscope and BaseScope™ in situ hybridization.

Presenter: Christopher Bunker Ph.D.

Using BaseScope™ Assay for Evaluation of Ocular Biodisribution of Gene Therapy Products

Watch the webinar and learn how Julio D. Nieves from Adverum (clinical-stage company) used the BaseScope™ ISH assay from Advanced Cell Diagnostics (a Bio-Techne company) to view biodistribution and validate their gene therapy candidates for a highly prevalent ocular disease with the aim to develop functional cure and restore vision and prevent blindness.

Presenter: Dr. Julio Nieves, ADVERUM

RNAscope™ Plus smRNA-RNA Assay

Advanced Cell Diagnostics miRNAscope ISH technology has become the gold standard for identifying the cellular localization of endogenous miRNAs and measuring delivery efficiency of therapeutic oligonucleotides in preclinical animal model systems. Combining proprietary RNAscope and miRNAscope ISH technologies, we are now introducing the RNAscope Plus smRNA-RNA assay which is a valuable new tool to quantify changes in gene expression and cellular function in response to the introduction of regulatory RNAs, essential for optimization of therapeutic efficacy and safety.