The RNAscope™ technology is being routinely used for tissue-based gene expression analysis for cancer research applications. In particular, the ultra-high sensitivity and specificity enables researchers to examine tumor heterogeneity within the tumor and in the tumor micro-environment. This technology, with its capacity to provide single-cell and single-RNA molecule sensitivity in the context of the tumor, has advanced cancer research and has been applied in over 800 publications.

Faraia Shah will present an overview on:

Visualizing gene expression and genetic variations in cancer research using RNAscope™ and BaseScope™ Assays

• Detect mRNAs and lncRNAs at single molecule sensitivity by RNAscope™ assay
• Target specific splice junctions for aberrant alternative splicing in cancers by BaseScope™ assay
• Characterize expression profiles of various cancer markers in tumors and micro-environment
• Case studies with PDL1, EGFR and other cancer markers will be discussed.