Push Boundaries with The New Breakthrough Technology for ASO, miRNA, and siRNA Detection

Detections of small non-coding RNAs such as microRNAs and short oligonucleotide therapeutics such as ASO and siRNA require a robust, highly specific and sensitive assay with minimal time and effort, , delivering data for easy interpretation. While microarrays and PCR both provide useful molecular profiles of diseases, important clinically relevant cell and tissue context information is lost along with the spatial variation of gene expression patterns. The miRNAscope™ Assay is a highly sensitive and specific in situ hybridization assay that allows for the visualization of ASO, miRNA, siRNA and other nucleic acid targets between 17-50 nucleotides expression in intact tissues or cultured cells with single-cell resolution, preserving spatial and morphological context.

The miRNAscope™ Assay is available for both the manual and automated (Leica Systems, LS) platforms.

The miRNAscope™ HD Manual AssayThe miRNAscope™ LS Assay


“Our experience working with ACD Bio has been all-around excellent. With their expertise and through clear communication, we developed several assays to detect both RNA and short oligonucleotides in tissue. Compared to standard complementary probes, the signal we obtained using ACD Bio was evident and specific. After seeing the first images, we immediately knew we wanted to use these techniques more frequently."

            --Exicure, R&D Team


“We had a great experience using miRNAscope™ in our compound screening efforts. The technique is incredibly specific and the results are very easy to understand. Also, working with ACD’s team has been extremely beneficial. They communicated with us during the process to ensure we can get the answers to our questions. They generated impeccable tissue stainings!

           --A leading BioPharma company in NY, USA



RNA ISH assay to detect ASO, miRNA, or siRNA

Download Brochure



Sensitive assay for ASO and siRNA Detection

Download Flyer


App Note

Introducing the novel miRNAscope™ in situ hybridization assay for the robust detection of microRNAs and other small RNA targets with spatial resolution

Download App Note



Download App Note



miRNAscope™ : a novel in situ hybridization technology for the detection of small regulatory RNAs with spatial and morphological context

Download Poster



Contact Us

Complete one of the three forms below and we will get back to you.

For Quote Requests, please provide more details in the Contact Sales form below

Advanced Cell Diagnostics

Our new headquarters office starting May 2016:

7707 Gateway Blvd.  
Newark, CA 94560
Toll Free: 1 (877) 576-3636
Phone: (510) 576-8800
Fax: (510) 576-8798



19 Barton Lane  
Abingdon Science Park
OX14 3NB
United Kingdom
Phone 2: +44 1235 529449
Fax: +44 1235 533420


Advanced Cell Diagnostics China

20F, Tower 3,
Raffles City Changning Office,
1193 Changning Road, Shanghai 200051

Web: www.acdbio.com/cn

For general information: Info.ACD@bio-techne.com
For place an order: order.ACD@bio-techne.com
For product support: support.ACD@bio-techne.com
For career opportunities: hr.ACD@bio-techne.com