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Probes for HER2

ACD can configure probes for the various manual and automated assays for HER2 for RNAscope Assay, or for Basescope Assay compatible for your species of interest.

ACD’s data images for HER2 gene.

  • Expression of HER2 in Human Bladder cancer sample using RNAscope™ 2.0 HD Assay Brown

Your search for "HER2" returned results. Search for our Top genes LGR5, vglut2, gad67, brca1

    Refine Probe List

    Content for comparison

    Gene

    • ERBB2 (29) Apply ERBB2 filter
    • HER2 (16) Apply HER2 filter
    • TBD (5) Apply TBD filter
    • CK19 (2) Apply CK19 filter
    • ACTB (1) Apply ACTB filter
    • AGTR1 (1) Apply AGTR1 filter
    • AREG (1) Apply AREG filter
    • PHLDA1 (1) Apply PHLDA1 filter
    • GAPDH (1) Apply GAPDH filter
    • CXCL10 (1) Apply CXCL10 filter
    • EGFR (1) Apply EGFR filter
    • IGKC (1) Apply IGKC filter
    • DUSP6 (1) Apply DUSP6 filter
    • Tbp (1) Apply Tbp filter
    • POLR2A (1) Apply POLR2A filter
    • HPV E6/E7 (1) Apply HPV E6/E7 filter
    • (-) Remove AR-V7 filter AR-V7 (1)
    • PDL1 (1) Apply PDL1 filter
    • HB-EGF (1) Apply HB-EGF filter
    • ST8SIA2 (1) Apply ST8SIA2 filter
    • ST8SIA4 (1) Apply ST8SIA4 filter
    • HPV HR18 (1) Apply HPV HR18 filter
    • ERBB2-E15E17 (1) Apply ERBB2-E15E17 filter
    • ERBB2-E15E16 (1) Apply ERBB2-E15E16 filter
    • d16HER2 (1) Apply d16HER2 filter
    • WTHER2 (1) Apply WTHER2 filter
    • ERBB2-E17E18 (1) Apply ERBB2-E17E18 filter
    • HPV- E6 / E7 (1) Apply HPV- E6 / E7 filter
    • TG1 (1) Apply TG1 filter

    Product

    • RNAscope 2.0 Assay (1) Apply RNAscope 2.0 Assay filter

    Research area

    • Cancer (1) Apply Cancer filter

    Category

    • Publications (1) Apply Publications filter
    Detection of AR-V7 transcript with RNA in situ hybridization in human salivary duct cancer

    Oral Oncology

    2018 Jun 28

    Kang H, Antonarakis ES, Luo J, Zheng Q, Rooper L, De Marzo AM, Westra WH, Lotan TL.
    PMID: - | DOI: 10.1016/j.oraloncology.2018.06.026

    The androgen receptor (AR) is a nuclear steroid receptor that binds to testosterone and dihydrotestosterone and regulates the transcription of genes leading to cell growth, differentiation and survival. AR serves as an important oncogenic signal in prostate cancers and apocrine breast cancers. Salivary duct carcinoma (SDC) is a rare subtype of head and neck cancer that is defined by an apocrine phenotype, with AR positivity by immunohistochemistry (IHC) in up to 98% of cases [1]. A recent clinical trial with leuprorelin acetate and bicalutamide has shown promising activity with an overall response rate of 42% in AR-positive salivary gland cancers, but further analyses of clinicopathological factors or biomarkers including AR expression intensity, HER2 expression, EGFR expression and HRAS mutation did not show any significant association with outcomes [2].

    X
    Description
    sense
    Example: Hs-LAG3-sense
    Standard probes for RNA detection are in antisense. Sense probe is reverse complent to the corresponding antisense probe.
    Intron#
    Example: Mm-Htt-intron2
    Probe targets the indicated intron in the target gene, commonly used for pre-mRNA detection
    Pool/Pan
    Example: Hs-CD3-pool (Hs-CD3D, Hs-CD3E, Hs-CD3G)
    A mixture of multiple probe sets targeting multiple genes or transcripts
    No-XSp
    Example: Hs-PDGFB-No-XMm
    Does not cross detect with the species (Sp)
    XSp
    Example: Rn-Pde9a-XMm
    designed to cross detect with the species (Sp)
    O#
    Example: Mm-Islr-O1
    Alternative design targeting different regions of the same transcript or isoforms
    CDS
    Example: Hs-SLC31A-CDS
    Probe targets the protein-coding sequence only
    EnEmProbe targets exons n and m
    En-EmProbe targets region from exon n to exon m
    Retired Nomenclature
    tvn
    Example: Hs-LEPR-tv1
    Designed to target transcript variant n
    ORF
    Example: Hs-ACVRL1-ORF
    Probe targets open reading frame
    UTR
    Example: Hs-HTT-UTR-C3
    Probe targets the untranslated region (non-protein-coding region) only
    5UTR
    Example: Hs-GNRHR-5UTR
    Probe targets the 5' untranslated region only
    3UTR
    Example: Rn-Npy1r-3UTR
    Probe targets the 3' untranslated region only
    Pan
    Example: Pool
    A mixture of multiple probe sets targeting multiple genes or transcripts

    Enabling research, drug development (CDx) and diagnostics

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