Speakers:
Localization of viral genomic DNA and RNA transcripts using RNAscope™ technology
Sarah VanVickle-Chavez, Ph.D, Washington University, St. Louis
Visualize gene expression and genetic variations in the tissue environment with the RNAscope™ ISH technology
Jacqueline Gilberti, Ph.D, Advanced Cell Diagnostics, Inc.
RNAscope™ assay is a proprietary RNA in situ hybridization (ISH) assay based on ACD patented signal amplification and background suppression technology which advances RNA biomarker analysis in tissues and cells.
Using RNAscope™ assay you can:
- Detect single RNA molecule at single-cell resolution in a single-day
- Asses splice variants, highly homologous sequences, lncRNA, and targets lacking IHC antibodies
- Analyze tumor heterogeneity using Dual ISH-IHC and Multiplex assays
- Quantify your mRNA and lncRNA expression analysis in tissue.
This enables researchers to visualize genes that are expressed, localize where they are expressed in any complex tissue from any species. The RNAscope™ technology is proven and published in over 700 publications in various research areas such as neuroscience, immuno-oncology, infectious disease and stem cell. This technology is commonly used for dual ISH-IHC analysis, RNA-Seq validation, single-cell analysis, and recently introduce BaseScope™ assay makes detection of exon junctions and highly homologous targets also possible.
