areaSpecificAmplifies signal and simultaneously suppress noiseareaSensitiveDetects single RNA moleculesareaContextDetects RNA within conserved tissue or cell morphology
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Search RNAscope™ Control and Target Probes
Available for > 40,000 targets across > 400 species including gene families and signaling pathway targets. Probes for new targets available in 2 weeks.
Biopharma Feature
Detect, localize and quantify vector and therapeutic transgenes
With RNAscope™ and BaseScope™ Assays
Biopharma Feature
Visualize and quantify expression of multiple checkpoint and immune cell markers
With RNAscope™ and BaseScope™ Assays
Biopharma Feature
Assess drug safety with unmatched sensitivity and specificity for any target in any tissue for any species
With RNAscope™ Assays
Biopharma Feature
Species-specific gene expression profiling of patient-derived xenograft tumors
With RNAscope™ Assays
Fig 7: Detection of G protein-coupled receptors (GPCRs) in mouse brain hippocampus using the RNAscope™ Multiplex Fluorescent assay on Fresh Frozen tissue samples: Cnr1 (Green) and Drd1 (Red). Cells are counterstained with DAPI.
Fig 8: Fluorescent detection of ion channels. Detection of Asic1 (Green) and Kcnj3 (Red) in mouse brain hippocampus using the RNAscope™ Multiplex Fluorescent assay on Fresh Frozen tissue samples.
Fig 9: Detection of transcription factor immediate early gene and activity marker Cfos (Green) and GPCR Chrm3 (Red) in mouse hippocampus using the RNAscope™ Multiplex Fluorescent assay on Fresh Frozen samples. Cells are counterstained with DAPI.
Fig 10: Detection of the effector immediate early gene and plasticity marker Arc (Green) and GPCR Drd1 (Red) in mouse brain striatum using the RNAscope™ Multiplex Fluorescent assay on Fresh Frozen tissue samples.
Fig 11: Detection of G protein-coupled receptors (GPCRs) in normal mouse brain hippocampus using RNAscope™2.5 HD Duplex Chromogenic assay on FFPE tissue samples: Cnr1 (Red) and Drd1 (Green). Cells are counterstained with hematoxylin.
Fig 12: Detection of G protein-coupled receptors (GPCRs) in normal mouse brain hippocampus using RNAscope™2.5 HD Duplex Chromogenic assay on FFPE tissue samples: Cnr1 (Red) and Drd1 (Green). Cells are counterstained with hematoxylin.
What to Buy
Step-by-step instructions to help you find the right products and accessories, learn best practices and get the best results from your assay.
Let us run your Biomarker assays
Get high quality gene expression data in just a few weeks.
Work smarter - Not harder
Sigal et al. used 46 RNAscope™ probes to thoroughly characterize the gastric antral gland stem cell niche.
Mark the Pathway
Analyze all genes of a pathway with RNAscope™ ISH assays e.g. WNT/ β-catenin pathway | JAK/STAT signaling pathway | Akt Signaling Pathway.
Validate your data
Use RNAscope™ ISH as a validation tool applied downstream of discoveries made with NGS, Microarrays, NanoString nCounter.
Visualize the invisible
Use RNAscope™ assays to detect & visualize long non-coding RNA.
Stay curious for new discoveries
Use RNAscope™ assays to detect and characterize new markers and targets.
Combine for Divine
Analyze RNA and protein simultaneously with ISH & IHC on the same tissue section.
Get Advice from Experts
Watch webinars for tips & tricks or presentations from our customers.
Keep calm and read the famous manual
See all available manuals, check-lists and supporting literature.
Take cellfies not selfies
View examples of RNA visualization with our RNAscope™ products.
Reveal in true colors
Detect up to four targets - take advantage of the RNAscope™ multiplexing capability.
Enabling research, drug development (CDx) and diagnostics
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For Research Use Only. Not for diagnostic use. Refer to appropriate regulations. RNAscope is a registered trademark; and HybEZ, EZ-Batch and DNAscope are trademarks of Advanced Cell Diagnostics, Inc. in the United States and other countries. All rights reserved. ©2024 Advanced Cell Diagnostics, Inc.
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