MicroMatrices Announces Partnership Agreement with Advanced Cell Diagnostics
November 10, 2014

MicroMatrices Announces Partnership Agreement with Advanced Cell Diagnostics

MicroMatrices becomes preferred partner for preclinical use of ACD’s RNA ISH 

DUNDEE, UK, November 10, 2014:
MicroMatrices, a service provider specialised in high resolution cell type-specific analysis to characterise toxicological responses in different cell types in tissue, today announced a preferred partnership agreement with Advanced Cell Diagnostics, Inc. (ACD), a leader in the field of molecular pathology and developer of cell and tissue-based analysis tools.

MicroMatrices solves molecular toxicological problems using unique visualization and localisation technologies, adding resolving power to standard methodologies. Consisting of a highly skilled core of scientists networked to facilities of excellence across the United Kingdom, MicroMatrices is scalable, efficient and flexible. MicroMatrices offers innovative, collaborative, state of the art solutions for unique efficacy and safety requirements.

MicroMatrices has been well known for immunohistochemistry (IHC) staining and has recently become expert in the use of ACD’s RNAscope® Technology to detect RNA based biomarkers in situ. This has resulted in unique expertise in combined protein/RNA co-detection and co-localisation to offer clients an exceptional target visualisation capacity which can guide and/or corroborate mechanistic and mode of action studies. In recognition of MicroMatrices’ extensive experience in applying RNAscope in preclinical toxicology investigations for safety and efficacy, ACD has begun a preferred partnership program for the provision and/or development of preclinical applications of RNAscope Technology.

Dr Simon Plummer, Managing Director of MicroMatrices commented; "The power and versatility of RNAscope has been an invaluable tool to enable us to solve mode of action/efficacy/toxicity challenges for our clients in the pharmaceutical, agrochemical, and chemical industries. We are delighted to be partnering with ACD to promote the wider application of RNAscope technology in preclinical safety/drug development problem solving for our collaborators".

ACD's RNAscope assays represent a major technological advance for in situ RNA detection. For the first time, robust single RNA molecule detection is available for formalin-fixed, paraffin-embedded (FFPE) tissue offering quantitative molecular detection with morphological context in a single assay. Since their commercialisation three years ago, these assays have been adopted across the globe by major pharma biotech companies and leading research institutions for drug discovery, translational research, and the development of clinical and companion diagnostic tests.

“ACD has established high quality performance standards through RNAscope products and services and MicroMatrices is known for quality, service and expertise in the drug development community," said Dr Steve Chen, Chief Operating Officer of ACD.  "As ACD's install base is growing very rapidly in Europe, they are an ideal partner not only to extend our reach but also to solidify our commitment in service quality.”

Learn more about MicroMatrices and their services at www.micromatrices.com and about ACD and RNAscope technology atwww.acdbio.com.

About MicroMatrices
MicroMatrices solves molecular toxicological problems using unique visualisation/localisation technologies, adding resolving power to standard methodologies. Consisting of a highly skilled core of scientists networked to facilities of excellence across the UK, MicroMatrices is scalable, efficient and flexible. As leaders rather than followers, MicroMatrices offers innovative, collaborative, state of the art solutions for unique efficacy and safety requirements, throughout the life cycle of products.

Founded in 2011, MicroMatrices is built upon Dr Simon Plummer’s 20 years of toxicological research at major international centres of excellence in the USA (NIH Bethesda), Australia (Peter MacCallum Cancer Institute, Melbourne) and the UK (MRC Toxicology Unit, Leicester) and is based in Dundee, a centre for world class life science research and innovation. Find out more atwww.micromatrices.com.

About Advanced Cell Diagnostics
Advanced Cell Diagnostics, Inc. (ACD) is a leader in the emerging field of molecular pathology, developing cell and tissue‐based diagnostic tests for personalized medicine. The company’s products and services are based on its proprietary RNAscope® technology, the first automated multiplex chromogenic and fluorescent in situ hybridization platform capable of detecting and quantifying RNA biomarkers in situ at single‐molecule sensitivity. RNAscope assays are currently used by hundreds of customers, including all of the global top 10 pharmaceutical companies, world leading academic institutions and many cutting edge biotechnology companies to validate biomarkers for the management of cancer and other diseases.  ACD’s industrial partnerships provide the foundation for ACD to develop companion diagnostic tests in conjunction with partners’ targeted therapeutics. ACD also pursues internal programs to develop and commercialize proprietary diagnostic tests in cancer management. Learn more about ACD and RNAscope technology atwww.acdbio.com.

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